COMBATING THE SARS-COV-2 OMICRON (BA.1) AND BA.2 WITH POTENT BISPECIFIC ANTIBODIES ENGINEERED FROM NON-OMICRON NEUTRALIZING ANTIBODIES

Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies

Abstract The highly mutated and transmissible Omicron (BA.1) and Chest its more contagious lineage BA.2 have provoked serious concerns over their decreased sensitivity to the current COVID-19 vaccines and evasion from most anti-SARS-CoV-2 neutralizing antibodies (NAbs).In this study, we explored the possibility of combating the Omicron and BA.2 by

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Dendrimers for Drug Delivery

Dendrimers have come CERAMICS a long way in the last 25 years since their inception.Originally created as a wonder molecule of chemistry, dendrimer is now in the fourth class of polymers.Dr.Donald Tomalia first published his seminal work on Poly(amidoamine) (PAMAM) dendrimers in 1985.Application of dendrimers as a drug delivery system started in la

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Advances in T Cells Based on Inflammation in Metabolic Diseases

With the increasing incidence of metabolic diseases year by year and their impact on the incidence of cardiovascular diseases, metabolic diseases have attracted great attention as Powder Bronzers a major health care problem, but there is still no effective treatment.Oxidative stress and inflammation are the main mechanisms leading to metabolic dise

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